Knee Pain: Causes and Approaches
- Victoria Wermers, RN,MSN,FNP, PMHNP
- Oct 26, 2024
- 3 min read
Updated: May 19
From youth to old age, knee pain is a common problem. There are many causes, from sprains and strains to injuries and arthritis. Is it any surprise? Our knees take a LOT of stress. In fact,
according to WebMD, "they bear 80% of your body weight when you stand still and 150% or more when you walk across the room. In a 160-pound person, that’s 240 pounds of force [on your knees]!" That's a LOT of weight! As they grow older, most females are also more inclined than males to have arthritic knees due to lower estrogen. So, if you are a female, have gained too much weight, have spent your hours on your knees with toddlers, and have washed a million floors (as WE used to do) is it any wonder why your knees are garbage?
Knee Injury
When a knee is injured, several different things can happen:
Torn ACL
Torn Meniscus
Bursitis
Patellar Tendonitis
Fracture
Arthritis
Occasionally, arthritis develops after injury (post-traumatic arthritis), however, it is usually due to immune disease, genetics, or aging, or a combination of these.
Rheumatoid Arthritis: Besides injury, a person may suffer from an autoimmune disease like rheumatoid.
Osteoarthritis may be the culprit or even an infection.
Diagnosing knee pain can entail just an exam and X-ray, or it can entail other radiographic tests like CT scans, ultrasounds, MRIs, arthroscopies (looking into the knee with a scope), and sometimes, blood tests. Is it any wonder that the knees suffer like this?
General Approaches to Knee Pain
If your knee is very painful, you are unable to walk on it, there is a lot of swelling, discoloration, or deformity, or if you have numbness and tingling in your foot, you should have it checked by a healthcare provider (i.e., an urgent care that does X-rays). Otherwise, you can usually wait a day or two and practice the old acronym RICE:
R - rest (But intermittently move the knee and increase as tolerated)
I - Ice Packs (15 minutes on three to four times a day) - change to warm, moist packs after three days
C - Compression
E - Elevate
Consider using a knee brace
Avoid kneeling on the floor- If you must, use good knee pads.
Initial Treatment is Typically Over-the-Counter
NSAIDs (ibuprofen/Advil/Motrin) or naproxen (Aleve) - best over-the-counter anti-inflammatories. The advantage of naproxen is that you can take it every 8 hours (or every 12, depending on how you dose it). Acetylsalicylic acid (common: Aspirin) is also a good NSAID, which may help swelling but can make an injury bleed and, therefore, bruise more.
Acetaminophen/Tylenol (pain reliever), on the other hand, is not an anti-inflammatory but a pain reliever instead. This is also a good medication, but used long-term, it can cause liver problems. Again, consider alternating this with ibuprofen every few weeks or speak to your PCP about getting another prescription pain medication.
Topical:
Menthyl salicylate (an anti-inflammatory related to aspirin)
Voltaren/diclofenac
Considered Herbal and Other Natural Remedies

Prescriptive Treatments
High dose ibuprofen (800 mg)
Corticosteroids have lots of potential side effects, from ulcers to diabetes, to hypertension to insomnia, and sometimes downright psychosis, but they are great anti-inflammatories. Sometimes healthcare providers prescribe short-term, low-dose steroids for inflammation, but because of the potential side effects, it is good to consider some of the alternatives.
COX-2 inhibitors (common: celecoxib/Celebrex, meloxicam/Mobic) are anti-inflammatories. These are less likely to cause stomach problems than ibuprofen and other NSAIDs.
Opioids (short-term) - These are painkillers such as oxycodone or hydrocodone (combo opioids with Tylenol: Lortab, Percocet, and Vicodin) and Tramadol (i.e., Ultram). Because these are highly addictive, they are not the drug of choice for long-term pain.
Steroid injections at the site of a joint problem can reduce swelling and inflammation
Sometimes surgery
If the pain or inflammation is severe, not improving, or recurrent, see a healthcare provider (preferably an orthopedist).