Respiratory: Asthma, (Primula flos): for catarrh (excessive mucus buildup), congestion, bronchitis

Cardiovascular: Cardiovascular disease, intermittent claudication (arterial flow obstruction in the legs), high blood pressure

Eyes: Dry eye

Gastrointestinal: Gastric distress, worms, liver problems, hepatitis B

Genitourinary: Hot flashes, night sweats, PMS, breast pain, endometriosis, menopause

Musculoskeletal: Muscle cramps, gout, rheumatic arthritis, osteoporosis (taken with calcium and fish oil), osteopenia, psoriatic arthritis

Neurologic: Diabetic neuropathy (nerve pain), chronic fatigue, Alzheimer’s, multiple sclerosis

Skin: Wound healing, eczema, psoriasis, acne, dry skin, molluscum contagiosum, astringent

Mental Health: Stress headaches, ADHD

Cholesterol: May help lower cholesterol (LDL) and raise good cholesterol (HDL)

Cancer: May help liver cancer

Other: Fever reducer, anticoagulant, weight loss, Raynauds

                                                      *   *   *

SIDE EFFECTS: Headache, nausea, diarrhea, stomach upset, soft stools, acne, increased bleeding, dizziness, headache, decreased seizure threshold, rash, taste changes, weight gain, bloodthinning

CAUTION/CONTRAINDICATIONS: Bleeding disorders (may increase bleeding), seizure disorders (lowers seizure threshold), phenothiazines, blood thinners, and schizophrenia

FORMS: Tea, soft gels, oils. 

Recommended Brands

Solgar Evening Primrose Oil 1300 mg softgel 

BodyBio Evening Primrose Oil — NSF certified, order through Fullscript link 

Allergy Research Group EPO — NSF certified, order through Fullscript link 

Pure Encapsulations Evening Primrose Oil — NSF certified, order through Fullscript link

I only recommend herbal and supplement brands that meet high standards for safety, effectiveness, and transparency. I research each product before sharing. Some links are affiliate links, meaning I may earn a small commission if you buy through them, at no extra cost to you. It helps support this free site. Plus, these links often offer discounts, fast shipping, and helpful reviews.

Dosage

As directed on the product label.

Some clinical and consumer sources describe a wide range of herbal amounts and application methods, and many are not supported by strong evidence. Always follow the manufacturer’s instructions.

Evening primrose oil is available in capsules, softgels, and liquid oils. Traditional and consumer use varies widely depending on the purpose, and product strengths differ significantly. Many people use evening primrose oil in combination with other supplements such as omega‑3 fatty acids or vitamin D, depending on the intended use.

For detailed drug dosing and interaction information, refer to herbal dosing on the Epocrates website.

Traditional Use (General Information Only)

Evening primrose oil has been used traditionally for skin comfort, menstrual support, and general wellness. Traditional practices describe a variety of forms, including oils and capsules. These uses are based on historical and consumer experience rather than strong clinical evidence.

Borage oil and flaxseed oil also contain omega‑6 fatty acids and are sometimes used for similar purposes.

These reflect traditional and consumer uses, not evidence‑based medical treatments. Product formulations vary, so it is important to follow the manufacturer’s directions.

*Disclaimer: The material above is for informational purposes only. This information is not intended to diagnose, treat or cure a condition. The uses listed above are tentative; some have or are undergoing research trials, but many are not FDA-approved. It is essential that you investigate these supplements further before deciding to use them. Check interactions and contraindications on sites like Drugs.com or WebMD. Do not attempt to treat a serious condition like liver, kidney problems, high blood pressure, heart, cancer, diabetes, or thyroid issues without discussing it with a healthcare provider first. If you are pregnant, do not use supplements without discussing it with your healthcare provider.