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L-Theanine

About

OTHER NAMES: Theanine


HISTORY: L-theanine is an amino acid extracted from found in black and green tea discovered in 1949. Since that time, it has also been made synthetically as a supplement. Few studies back up the actions of L-theanine (below). It is thought to exert its action by boosting various neurotransmitters: GABA, serotonin, and dopamine.


CONSIDERED USES


Cardiovascular: High blood pressure


Respiratory: Flu, cold symptoms


Neurologic: Mental performance, ADHD (especially if taken with moderate caffeine), Alzheimer’s, cognitive decline/impairment (age-related), cognitive function, insomnia, Tourette’s


Mental Health: Tics, anxiety, depression, OCD, schizophrenia, stress


Cancer: Possibly helps


Side Effects: Low blood pressure, decreased appetite, digestive problems, headache, moodiness, problems concentrating, dizziness, jitteriness


Cautions/Contraindications: Possible interactions with some blood pressure medicines and benzodiazepines (Ativan, Xanax, and others) and sedating medications might also decrease the effects of stimulants


FORMS: Teas (especially matcha), capsules, tablets, powder, chewable


DOSAGES: As directed

The following are reported doses and may NOT be supported by evidence (reported by various sources, i.e., WebMD, RxList, Epocrates, ConsumerLabs, German Commission E). Read dosages and instructions carefully when available on the label.

  • General: 200-400 mg by mouth daily for 4 to 8 weeks (up to 500 mg)

  • Anxiety: 200 mg by mouth once daily

  • Attention: 100-400 mg by mouth daily

  • Cognitive function: 100-200 mg by mouth once daily

  • Depression: 250 mg by mouth at bedtime

  • Insomnia: 50 mg by mouth at bedtime (take one hour before bed)

  • Stress: 200 mg by mouth 1-2 times daily

  • Mental Acuity: 100 mg by mouth before a test (with caffeine)

*Disclaimer: The material above is for informational purposes only. This information is not intended to diagnose, treat, or cure a condition. The uses listed above are tentative; some have or are undergoing research trials, but many are not FDA-approved. You must investigate these supplements further before deciding to use them. Check interactions and contraindications on sites like Drugs.com or WebMD. Do not attempt to treat a serious condition like liver, kidney problems, high blood pressure, heart, cancer, diabetes, or thyroid issues without discussing it with a healthcare provider first. If you are pregnant, do not use supplements without discussing it with your healthcare provider.

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*Disclaimer: The material above is for informational purposes only. This information is not intended to diagnose, treat or cure a condition. The uses listed above are tentative; some have or are undergoing research trials, but many are not FDA-approved. It is essential that you investigate these supplements further before deciding to use them. Check interactions and contraindications on sites like Drugs.com or WebMD. Do not attempt to treat a serious condition like liver, kidney problems, high blood pressure, heart, cancer, diabetes, or thyroid issues without discussing it with a healthcare provider first. If you are pregnant, do not use supplements without discussing it with your healthcare provider.

© 2025 by Web Guide To Healthcare

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