Respiratory: Cough (expectorant)

Cardiovascular: Varicose veins

Gastrointestinal:  Hemorrhoids

Musculoskeletal: Joint pain. Osteoarthritis, rheumatoid arthritis, sprains, strains, bruises, gout, back pain (topical)

Skin: Decreases pain of wounds, burns, can increase callous formation

                                                       *   *   *

SIDE EFFECTS: See cautions below

CAUTIONS/CONTRAINDICATIONS: Oral comfrey can cause liver damage, lung damage and cancer. Do not apply to open wounds. Many European countries and the FDA have taken the oral comfrey products off the market due to their potentially toxic properties. Not to be taken with many anti-seizure medicines, rifampin, rifabutin

FORMS: External use: ointment, oils, powders, creams

Recommended Brands

No recommended brands are currently available.

Dosage

As directed on the product label.

This herb is used externally only. It should not be taken internally due to concerns about liver toxicity. Always follow the manufacturer’s instructions for topical application.

The German Commission E has evaluated this herb for external use and provides guidance on limiting duration of use. Their specific dosing instructions are proprietary and cannot be reproduced here, but traditional guidance recommends restricting use to short periods each year.

For detailed drug dosing and interaction information, refer to herbal dosing on the Epocrates website.

Traditional Use (General Information Only)

This herb has been used traditionally in topical preparations such as creams, ointments, and compresses. Traditional practices emphasize external use only, with attention to duration and product quality.

These reflect traditional and consumer uses, not evidence‑based medical treatments. Product formulations vary, so it is important to follow the manufacturer’s directions.

*Disclaimer: The material above is for informational purposes only. This information is not intended to diagnose, treat, or cure a condition. The uses listed above are tentative; some have or are undergoing research trials, but many are not FDA-approved. You must investigate these supplements further before deciding to use them. Check interactions and contraindications on sites like Drugs.com or WebMD. Do not attempt to treat a serious condition like liver, kidney problems, high blood pressure, heart disease, cancer, diabetes, or thyroid issues without discussing it with a healthcare provider first. If you are pregnant, do not use supplements without discussing it with your healthcare provider.